1Thurman RG, Bradford BU, Iimuro Y, et al. The role of gut-derived toxins and free radicals in alcohol-induced liver injury. J Gastroenterol Hepatol, 1998, 13:S39-50.
2Thurman RG. Alcoholic liver injury involves activation of Kupffer cells by endotoxin. Am J Physiol, 1998, 275:G605-611.
3Bode C, Schafer C, Fukui H, et al. Effect of treatment with paromomycin on endotoxemia in patients with alcoholic liver disease--a double-blind, placebo-controlled trial. Alcohol Clin Exp Res, 1997,21: 1367-1373.
4Fukui H, Brauner B, Bcde JC, et al. Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: reevaluation with an improved chromogenic assay. J Hepatol, 1991, 12:162-169.
5Adachi Y, Moore LE, Bradford B, et al. Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology,1995, 108:218-224.
6Parlesak A, Schafer C, Schutz T, et al. Increased intestinal permeability to macromolecules and endotoxemia in patients with chromic alcohol abuse in diffenrent stages of alcohol-induced liver disease. J Hepatol, 2000, 32:742-747.
7Draper LR, Gyure LA, Hall JG, et al. Effect of alcohol on the integrity of the intestinal epithelium. Gut, 1983, 24: 399-404.
8Bautista AP. Impact of alcohol on the ability of Kupffer cells to produce chemokines and its role in alcoholic liver disese. J Gastroenterol Hepatol, 2000, 15:349-356.
9Schafter C, Greiner B, Landing J, et al. Decreased endotoxin-binding capacity of whole blood in patients with alcoholic liver disease. J Hepatol, 1997, 26:567-573.
10Tuslamoto H, Lin M, Ohata M, et al. Iron primes hepatic macrophages for NF-kappaB activation in alcoholic liver injury. Am J Physiol, 1999, 277:G1240-1250.
