摘要
研究了4,4′-联苯二甲酸的合成工艺。以联苯为原料,经烷基化、水解反应制得4,4′-二(氨甲基)联苯盐酸盐,继而经Sommelet和氧化反应合成出4,4′-联苯二甲酸,总收率达到60.2%(以联苯计),纯度>98.0%,产物和中间体的结构经元素分析和核磁共振加以确证,对其反应条件进行了优化。工艺各步反应操作简单,原料易得,反应条件温和,具有一定的工业应用价值。
To prepare Biphenyl-4,4′-dicarboxylic acid,4,4′-Bis(aminomethyl)biphenyl hydrochloride was synthesized from biphenyl by alkylation and hydrolysis,then it underwent Sommelet reaction and oxidation to reach the overall yield of 60.2% and purity of 99.0%.The optimal reaction conditions were also studied,and 1H NMR and elementary analyses confirmed the structures of products.This method has potential application in the field of liquid crystals polymer materials.
出处
《江苏化工》
2008年第4期18-20,共3页
Jiangsu Chemical Industry
基金
淮海工学院自然科学研究基金资助项目(Z2006003)
江苏省江苏高校高新技术产业发展项目(JHB05-50)
关键词
联苯
4
4'-联苯二甲酸
合成
biphenyl
Biphenyl-4,4′-dicarboxylic acid
synthesis