塑料电泳芯片的结构设计

Design of Structure for Plastic Capillary Electrophoresis Chips

本文分析了电泳芯片常用材料的性能、不同微通道网络形状和尺寸参数对分离性能的影响 ,并在此基础上概述了塑料电泳芯片材料的选取以及微通道网络形状和尺寸参数的确定方法 ,以期为建立毛细管电泳芯片结构设计、制作和深入研究的技术平台奠定基础。

A plastic capillary electrophoresis chip is a novel kind of miniaturized device for biochemistry analysis. The major advantages of the chip include low conductivity for electrokinetic pumping and electrophoretic separation; low cost for high volume production and disposal and easily manufacturing for high aspect ratio of microchannels on the chip. In this paper, properties of materials used for the chip and effects of network geometries and dimensions of the micro channels on the separation performance are analyzed, based on these, basic ways of selecting materials for the chip and designing network geometries and dimensions of the micro channels are introduced. Which establishes the technical foundation for structural design, fabrication and deep study of the chip.