陈旧性骨质疏松骨折疼痛治疗的对比研究

The Comparative Study of the Treatment on Old Osteoporotic Fracture Patient with Acute Pain

目的探讨老年骨质疏松骨折患者疼痛治疗的有效方法,分析比较降钙素和低频脉冲电磁场对老年骨质疏松骨折疼痛的临床效果。方法92例老年陈旧性骨质疏松骨折疼痛患者随机分成2组,降钙素治疗组(A组):鳗鱼降钙素肌注20u/d,第一周1次/d,以后2次/w;低频脉冲电磁场治疗组(B组):低变频、宽幅、多部位脉冲电磁场治疗5次/d,30min/次,15次后休息1w,4w为1个疗程,各组治疗时间为半年。随访分别于治疗前,治疗1、2、4月和6月时评估疼痛强度和缓解度,骨密度(DXA)和骨强度(QUS)分别于治疗前和治疗结束时测定。结果降钙素和低频脉冲治疗对老年陈旧性骨质疏松骨折疼痛有显著的缓解作用,治疗1月后疼痛强度明显下降(P<0.01);治疗6月疼痛逐渐缓解。结论降钙素和低频脉冲电磁场治疗老年陈旧性骨质疏松骨折疼痛临床疗效类似,可有效缓解疼痛。

Objective To evaluate the effective methods on elderly osteoporotic fracture patient with acute pain.Comparing and analysis the therapeutic effect of calcitonin and pulsed electromagnetic fields on osteoporotic fracture patient with acute pain. Methods 92 elderly osteoporotic fracture patients with acute pain were divided into 2 groups by random, Calcitonin treatment group (group A):Elcitonin intramuscular 20u/day,the patients were accepted treatment once everyday on the first week,then twice a week;Low-frequency pulsed electromagnetic field therapy group (group B):Low-frequency pulsed electromagnetic fields were used:low-frequency,broad width,and multifields,one course of treatment will last four weeks,on beginning three weeks of every course,the patients were accepted treatment five times(thirty minutes every time) every week,and rest for one week after fifteen times' treatments.Every group has half year treatment,then we respectively take the evaluation of the algetic strength and catabatic degree before treatment and the one month,two month,four month and six month of treatment. Bone mineral density(DXA) and bone strength (QUS) respectively Measure before treatment and at the end of treatment. Results Low-frequency pulsed electromagnetic fields and Calcitonin had marked anesis effect on the acute pain of elderly osteoporotic fracture patient,algetic strength obviously decreased after four weeks(P<0.01);in the six month cure process the ache alleviate gradually. Conclusion The clinical curative effect of calcitonin and the low frequency pulse electromagnetism field curing elderly osteoporotic fracture patient with acute pain is similar,they both can alleviate ache effectively.