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抑郁症诱发电位波形变异与自杀行为史的关联性研究

Study of Correlation between Sensory Evoked potential Amplitude Variations and Suicidal Behavior in Patients with Depression Disorder
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摘要 目的 探讨抑郁症患者脑诱发电位(BEP)波幅下降与自杀行为史的关系以及临床意义.方法 应用美国尼高力公司Spirit脑诱发电位仪,记录了39例抑郁相、22例躁狂相患者和33名正常对照者的3种诱发电位.结果 1.与正常对照组相比,抑郁相和躁狂相组均出现诱发电位主成分波幅降低,抑郁相VEP/P2潜伏期延迟(正常对照组(194±19)ms,自杀史阳性组(211±21)ms,自杀史阴性组(209±17)ms, P<0.01).2.两组患者的SEPs改变主要与患者有无自杀行为史有关.结论 诱发电位临床应用价值得到了初步证实,与自杀行为相关的生物学指标研究中需进一步重视.
出处 《神经病学与神经康复学杂志》 2007年第4期223-225,共3页 Journal of Neurology and Neurorehabilitation
基金 上海市精神卫生中心课题
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