期刊文献+

他汀类药物预防缺血性卒中/TIA的安全性 被引量:2

Safety of Statins on the Prevention of Ischemic Stroke/TIA
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摘要   他汀类药物(statinS),也称3-羟基3甲基戊二酰辅酶A(3-hyd rOXy-3-methylglutaryl-coenzyme A,HMG-CoA)还原酶抑制剂.他汀类药物可竞争性抑制细胞内胆固醇合成早期过程中限速酶的活性,继而上调细胞表面低密度脂蛋白(LDL)受体,加速血浆LDL的分解代谢;此外,他汀类药物还可抑制极低密度脂蛋白(VLDL)的合成.……
出处 《中国卒中杂志》 2007年第4期332-334,共3页 Chinese Journal of Stroke
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参考文献12

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同被引文献26

  • 1曹红,孙长凯,赵杰,赵耿毅,唐树良,汪秋艳,侯宇,许晶,陶定波,刘新胜,黄爱莉.他汀类药物对脑梗死患者神经功能缺损及血清相关参数的影响[J].中国临床康复,2005,9(9):94-96. 被引量:25
  • 2赵水平,吴军,谭利明,胡治平,肖志杰,聂赛,周宏年,蒋波.他汀类药物对急性脑梗死的抗炎作用[J].中华医学杂志,2005,85(40):2841-2845. 被引量:48
  • 3刘树琴.2型糖尿病与炎症及他汀类药物[J].实用糖尿病杂志,2006,2(2):9-10. 被引量:9
  • 4余昌胤,袁胜山,张骏.辛伐他汀对大鼠脑缺血再灌注后脑组织NOS表达的影响[J].贵州医药,2006,30(12):1069-1071. 被引量:5
  • 5McMurray J J V,Kjekshus J,Gullestad L,et al. Effects of statin therapy according to plasma high-sensitivity C-reac- tive protein concentration in the controlled rosuvastatin multinational trial in heart failure (CORONA).A retrospec- tive analysis[ J ]. Circulation, 2009 (120) : 2188-2194.
  • 6Chou T C,Lin Y F,Wu W C,et al. Enhanced nitric oxide and cyclic GMP formation plays a role in the anti-platelet activity of simvastatin[J]. BrJ Pharmacol,2008,153(6): 1281-1287.
  • 7Undas A,Brummel K E,Musial J,et al. Simvastatin depressesblood clotting by inhibiting activation of prothrombin,factor V, and factor X II and by enhancing factor Va inactivation [ J ]. Circulation, 2001 ( 103 ) : 2248 - 2253.
  • 8LaRosa J C,Grundy S M,Waters D D,et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease[J]. N Engl J Med,2005,352( 14): 1425-1435.
  • 9Ebrahim S,Sung J,Song Y M,et al. Serum cholesterol, haemorrhagic and ischemic stroke and myocardial infarction: Korean national health service prospective cohort study[J] BMJ,2005(333) :22.
  • 10Amarenco P, Labreuehe J, Lavallee P, et al. Statin in stroke prevention and carotid atheroselerosis:systematie review and met.a-analysis[ J ]. Stroke, 2004(35 ) : 2902-2909.

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