摘要
脑血管储备包括血流储备、功能储备、结构储备、化学储备及代谢储备等。脑血管储备能力的高低在卒中的发生、发展及转归中具有重要的作用。已证实脑血管储备能力强的患者,卒中后的转归较好。尤瑞克林是组织型激肽原酶1,作为激肽原酶-激肽系统的一个正向调节物质,它能水解激肽原释放激肽,作用于激肽受体,从而发挥多种生理作用。脑梗死时给予尤瑞克林,对血管的舒缩程度,组织血供、氧供、能量代谢及血流动力学等多个方面均有改善作用,能够通过提高卒中患者的脑血管储备能力来改善预后。
Cerebrovascular reserve capacity includes cerebral perfusion reserve,functional reserve,structure reserve,chemical reserve and metabolic reserve. Cerebrovascular reserve capacity plays an important role during onset,progress and prognosis in patients with stroke. Urinary Kallidinogenase(human urinary kallikrein) is a positive regulatory substance in Kallikrein-Kinin system(KKS) which could improve the cerebral perfusion and energy metabolism. Urinary Kallidinogenase might improve prognosis for stroke patients by increaing the cerebrovascular reserve capacity.
出处
《中国卒中杂志》
2007年第6期545-548,共4页
Chinese Journal of Stroke
关键词
脑血流储备
尤瑞克林
Cerebrovascular reserve
Urinary kallidinogenase
