摘要
目的观察左旋卡尼汀治疗对急性心肌梗死患者心功能的影响。方法68例急性心梗患者,随机分成治疗组及对照组,除常规治疗外,治疗组加左旋卡尼汀治疗2周。分别测量心梗后第1周、第4周、第12周患者的左室射血分数(LVEF)以及第4周、第12周患者6min步行试验。结果治疗后第12周两组患者LVEF和6min步行试验结果较治疗前已有明显恢复(P<0.001);而左旋卡尼汀治疗组的患者,较对照组亦提高,差异有显著性(P<0.05)。结论左旋卡尼汀有助于急性心肌梗死患者心功能的恢复。
Objective To observe the effect of L- camitine(L- CN)on the heart function of patients with acute myocardial infarction (AMI) .Methods 34 cases with AMI randomly received routine treatment and other 34 cases with AMI added the L - CN with routine treatment in two weeks,to measure the LVEF at the end of the 1st week,4th week and 12th week and 6 minutes walk test at the end of the 4th week and 12th week.Results There was significant difference in heart function changes in two groups before and after treatment ( P < 0.01). Conclusion L - CN with routine therapy might be an effective and safe way to renew the heart function of the patients with AMI.
出处
《中国实用医药》
2007年第5期22-24,共3页
China Practical Medicine
关键词
急性心肌梗死
左旋卡尼汀
心功能
Acute myocardial infarction
L- carnitine
Heart function