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辛伐他汀治疗冠心病合并高脂血症疗效观察

Combination therapy of Simvastatin treating Coronary heart disease patients with Hypercholesterolemia
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摘要 目的观察辛伐他汀治疗冠心病并高脂血症的临床治疗效果。方法选取90例冠心病并原发性高脂血症患者,每晚服用辛伐他汀20mg,疗程6周,观察血脂变化。结果治疗6周后总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)较治疗前显著下降(P<0.01),高密度脂蛋白胆固醇(HDL-C)也明显升高(P<0.05)。结论辛伐他汀降脂疗效确切,不良反应少,安全可靠。 Objective To investigate the effect of Simvastatin treating Coronary disease patients with Hypercholesterolemia. Methods Ninety patients with Simvastatin treating Coronary disease with Hypercholesterolemia, Using Simvastatin 20 mg qn,treating 6 weeks.Be observed blood lipid chang. Results After treating 6 weeks ,TC、TG、LDL-C evident down (P<0.01),HDL-C evident rise(P<0.05).Conclusion Simvastatin reduce lipid evidevt quick and secure.
出处 《中国实用医药》 2007年第12期9-10,共2页 China Practical Medicine
关键词 辛伐他汀 冠状动脉疾病 高胆固醇血症 Simvastatin Coronary disease Hypercholesterolemia
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  • 1[1]The Scandinavian Simvastatin Survival Group.Randomized trial of chole-sterol lowering in 4 444 patients with coronary heart disease:The Scandinavian Simvastatin Survival Study (4S)[J].Lancet,1994,344:1383-1389.
  • 2[2]Shepherd J,Cobbe S M,Ford I,et al.Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia[J].N Engl J med,1995,333(20):1301-1307.
  • 3[3]Jukema J W,Onbehalf to the REGRESS study group,InterUniversity Cardiology.Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels.The Regression Growth Evaluation Statin Study (REGRESS)[J].Circulation,1995,91:2528.
  • 4[4]Aikawa M,Rabkin E,Voglic S J,et al.Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma:a potential mechanism of lesion stabilization[J].Circulation,1998,95:2433-2444.
  • 5[5]MAAS Investigators.Effects of simvastatin on coronary atheroma:the multicentre anti-atheroma study (MAAS)[J].Lancet,1994,344:633.
  • 6[6]Crouse J R.Pravastatin,Lipids and atherosclerosis in the carotid arteries (PLAC-Ⅱ)[J].Am J Cardiol,1995,75:455-459.

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