35例老年念珠菌性食管炎的诊断与治疗

目的为研究老年念珠菌性食管炎的诊断与治疗。方法本组35例均经电子胃镜检查,病理证实,依食管黏膜损害程度分级。随机分两组,18例口服三联法(雷尼替丁、盐酸黄连素、西沙必利)治疗,17例口服制霉菌素治疗,14d为1个疗程。经内镜、病理复检无显示念珠菌为治愈。结果三联法治愈占94.44%,制霉菌素占64.71%。经统计学处理结果表明,三联法治愈率优于克霉唑组(χ2=4.833,P<0.05)。结论三联法是治疗念珠菌性食管炎的有效方法,适宜推广。

Objective To study the diagnosis and treatment of candida esophagitis in elderly patients.Methods 35 cases patients were examed by electric endoscopic and pathologic dignosis according to mucosa damage.They were divided into 2 groups:the triad-therapy group of 18 cases given triad-therapy(Cimetidine,berberine hydrochloride and Cisapride),and Ciotrimazole group(17 cases)given Ciotrimazole-therapy for 14 days as one course of treatment.Results The cure rate was 94.44% in triad-therapy group and was 64.71 % in Candistatin group.The cure effect of triad-therapy was better than the other group,and it had great difference(χ2=4.833,P<0.05).Conclusion Triad-therapy had well effect on candida esophagitis,and it's easily to spread.