2,2-二甲基-5,5-二乙氧羰基-1,3-二氧六环的合成
Synthesis of 2,2-Dimethyl-5,5-bis(ethoxycarbonyl)-1,3-dioxane
摘要
以丙二酸二乙酯为原料,对2,2-二甲基-5,5-二乙氧羰基-1,3-二氧六环的合成进行了研究。
The synthesis of 2,2-dimethyl-5,5-bis(ethoxycarbonyl)-1,3-dioxane is studied,with diethyl malonate as the main material in this paper.
出处
《山东化工》
CAS
2007年第7期8-9,共2页
Shandong Chemical Industry
参考文献9
-
1郭丽,翁玲玲,郑虎.四方向、六方向醚键型分枝状化合物的合成[J].有机化学,1996,16(6):539-543. 被引量：4
-
2[2]EImar Bosies,Dieter B J Herrmann,Uwe Bicker,et al.Synthesis of Thioether Phosphocholine Analogues[J].Lipids,1987,22:947～951.
-
3[3]Wei Yuan,Richard J Berman,Michael H Gelb.Synthesis and evaluation of phospholipid analogs as inhibitors of cobra venom phospholipase A2[J].J Am Chem Soc,1987,109:8071～8081.
-
4李佩杰,徐正,伍晓春,吴勇.2,2-二甲基-5-羟甲基-1,3-二氧六环的合成[J].华西药学杂志,2001,16(4):276-276. 被引量：2
-
5[5]Paul Block Jr,Melvin S Newman,Reinhardt Stein.Diethyl bis(hydroxymethyl)malonate[J].Organic Syntheses,1973,5:381.
-
6[6]Welch K N./XXXVIII-The reactions of malonic esters with formaldehyde:Part I[J].J Chem Soc,1930:257～261.
-
7[7]Ferris A F.The action of mineral acid on diethyl bis-(hydroxymethyl)malonate[J].J Org Chem,1955,20:780～787.
-
8[8]Mikko Ora,Esa Mki,Pivi Poijrvi,et al.Hydrolytic stability of nucleoside phosphotriesters derived from bis(hydroxymethyl) -1,3-dicarbonyl compounds and their congeners:towards a novel pro-drug strategy for antisense oligonucleotides[J].J Chem Soc:Perkin Trans 2,2001:881～885.
-
9[9]Gault H,Roesch A.Diethyl bis(hydroxymethyl)malonate[J].Bull Soc Chim France,1937,5(4):1410～1441.
共引文献3
-
1付永举,王建平,李延红,韩民乐.迈克尔加成法合成乙二胺枝状化合物[J].化学研究,2005,16(4):27-29.
-
2盛继文,刘冬梅,王思宏.2,2-二甲基-5,5-二乙氧羰基-1,3-二氧六环的合成[J].德州学院学报,2007,23(6):42-44.
-
3吴勇,季涛,郑虎.多官能团分枝状化合物的合成研究——Ⅸ.几个分支侧链的合成[J].华西医科大学学报,1999,30(1):37-39. 被引量：2
