摘要
采用乙醇-水体系精制头孢曲松钠,收率可达94%,产品流动性与晶型得到大幅度改善,产品质量和稳定性也有较大提高。所得产品在温度40℃,相对湿度75%条件下做加速实验2个月,产品质量也表现出良好的稳定性,产品质量符合CP2005标准要求。
To recrystal ceftriaxone sodium in ethanol-water solution,the yield of 94 percent was reached,good flowablity and crystallization were largly improved and its good quanlity and stability were showed.Although the product made by this method was stored under the temperature of 40℃ and humidity of 75% for two months,its stability was good and the quality of product conformed to CP2005.
出处
《山东化工》
CAS
2007年第10期7-8,11,共3页
Shandong Chemical Industry
关键词
头孢曲松钠
精制
结晶
ceftriaxonesodium
recrystallization
cryctallization
