乌司他汀和生长抑素联合应用治疗急性胰腺炎临床疗效观察

目的观察乌司他汀和生长抑素联合应用治疗急性胰腺炎的临床疗效。方法急性胰腺炎27例,乌司他汀20万U加5%葡萄糖500ml静脉滴注,2次/d,连用10～14天。生长抑素0.1mg,1次/8h皮下注射,连用10～14天。结果轻型胰腺炎有效率94.1%,重症胰腺炎有效率60.0%,总有效率81.5%。结论乌司他汀和生长抑素联合应用可有效抑制胰酶的释放,阻止急性胰腺炎病程的发展。

Objective To observe clinical effects of Ulinastatin and Sandostain on treating acute pancreatitis. Methods 27 cases with acute pancrealitis were treated with Ulinastatin 200 000U+5% glucose injection 500ml two times a day and Sandostain hypodermic injection 0.1mg every 8h.Time of treatment was 10 to 14 days. Results The effective rate was 94.1% in light type,60.0% in severe type and total effective rate was 81.5% in 27 acute pancreatitis. Conclusions Ulinastatin and Sandostain can evidently inhibit the production of pancreatogenous enzymes and hold back the development of acute pancreatitis.