颈内动脉粥样硬化斑块与短暂性脑缺血发作的关系

Relationship between transient ischemic attack and atherosclerotic plaques in carotid attery

目的探讨颈动脉粥样硬化斑块与短暂性脑缺血发作(TIA)发生的关系。方法应用多普勒超声技术检测了64例颈内动脉系TIA患者颅外颈动脉,检测分析指标为颅外颈动脉硬化板块斑块的分布、狭窄度及超声分型。并将有症状侧与无症状侧进行比较研究。结果TIA患者无症状侧颅外颈动脉中度以上狭窄发生率(29.69%)明显高于有症状侧(10.94%),差异有显著意义(P<0.01);TIA患者颅外颈动脉硬化斑块以扁平斑最为多见,其次为硬斑和溃疡斑,且无症状侧软斑发生率明显高于有症状侧,差异有显著意义(P<0.01)。结论颅外颈动脉粥样硬化是TIA发生的重要危险因素,这一发现对于临床上预测无症状人群TIA的发生有重要价值。

objective To investigate the relationship between atherosclerotic plaques carotid artery and transient ischemic attack(TIA). Methods Useing doppler ultrasound to assess extracranial carotid ateries in 64 cases of TIA. The evaluating items are atherosclerotic plaque location stenosis, classification in extracranial carotid artery, meanwhile, comparation between symptomatic side and asymptomatic side.Results The incidence(29.69%)of over middle-grade stenosis on asymptomatic side in extracranial internal carotid artery(EICA) in group of patients of TIA is obviously higher than symptomatic side(10.94%).The difference is signifficant(P<0.01). Flat plaque and soft plaque are the most common ones in group of patients of TIA. The incidence of soft plaques on asymtomatic side is obviously higher than symptomatic side.The difference is significant(P<0.01). Conclusions Atheroderotic plaques in carotid is the important dangerous factor of TIA causing these findings which have important value in predicting subsequence TIA in asymptomatic subjects.