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院内肺炎和呼吸机相关肺炎的抗菌药物应用

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摘要 医院内获得性肺炎包括呼吸机相关肺炎,根据发病时间的不同,是否伴有危险因素,是否存在多重耐药病原体的感染,抗菌药物的选择和治疗预后等方面都不同。正确选用抗生素是治疗HAP、VAP的关键。现临床常用的选药方法,根据临床的诊断过程大致可分为两个阶段:病原体尚不明确时的经验性选用和致病菌明确后的选用。早期、适当的初始经验性抗生素治疗,对于改善临床治疗结果很重要,初始经验性抗生素治疗时,应选择广谱、高效抗生素以覆盖所有可能致病菌的药物,包括革兰阴性菌和阳性菌。待得到病原学报告后再选针对性的窄谱抗生素,本文主要参考2005年美国胸科学会发表的HAP与VAP新指南,介绍了目前HAP与VAP的抗生素治疗情况。
作者 张晓军
出处 《中国药物应用与监测》 CAS 2006年第4期36-41,共6页 Chinese Journal of Drug Application and Monitoring
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参考文献9

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