脂肝合剂治疗痰瘀互结型脂肪性肝病的临床研究

Clinical Study on Zhigan Heji for Treatment of Fatty Liver Disease Due to Combined Phlegm and Blood Stasis

目的:观察脂肝合剂治疗痰瘀互结型脂肪性肝病的临床疗效。方法:将60例痰瘀互结型脂肪性肝病病例分为治疗组(30例)和对照组(30例),分别给予脂肝合剂和甘乐片治疗,疗程3个月。观察患者临床症状、体征以及肝功能、血脂和肝脏B超等项目。结果:治疗组总有效率为93.33%,对照组总有效率为83.33%。在改善临床症状体征、恢复肝功能、减轻肝脏炎症反应方面,脂肝合剂疗效优于甘乐片(P<0.05),而在降低血脂方面疗效与甘乐片相似(P>0.05)。结论:脂肝合剂为治疗痰瘀互结型脂肪性肝病的有效药物。

Objective:To observe Clinical curative effect of Zhigan Heji for the treatment of fatty liver due to combined phlegm and blood stasis.Methods:60 cases of fatty liver due to combined phlegm and blood stasis were randomly divided into treatment group(30 cases,treated by Zhigan Heji) and control group (30 cases,treated by Diisopropylamine).The course of treatment lasted for three months.The clinical symptoms,physical signs,liver function,blood fat and type B ultrasonic of liver,etc. of the patients were observed.Results:The total effective rate of the treatment group was 93.33%,while that of the control group was 83.33%.Besides,Zhigan Heji is better than Diisopropylamine in improving clinical symptoms and physical symptoms,repairing liver function and relieving hepatitis(P<0.05),but their curative effect on reducing blood fat didn’t show significant difference(P>0.05).Conclusion:Zhigan Heji is an effective medicine for treatment of fatty liver due to combined phlegm and blood stasis.