抗生素在晚期先兆流产治疗中的意义

目的探讨抗生素在晚期先兆流产保胎治疗中的应用价值。方法选择妊娠中期(13-27周)发生先兆流产孕妇256例随机分为两组,研究组126例,连续使用3天抗生素安胎治疗。对照组130例,不使用抗生素安胎治疗,检测治疗前、治疗3天后血中白细胞计数(WBC)及C-反应蛋白(CRP)值。结果①研究组治疗前后CRP比较,P<0.05,有显著差异,WBC比较,P>0.05, 无显著性差异。对照组治疗前后WBC,CRP比较,P>O.05,无显著性差异。②研究组安胎成功101例,占80.2%,对照组安胎成功81例,占63.1%。比较两组成功率,P<0.05,有显著差异。结论在晚期先兆流产保胎中使用抗生素效果显著,血清CRP有助于预测妊娠结局。

objective To study the value of using antibiotics in the preventing miscarriage theory for the late treatment abortion. Methods 256 pregnant women in the Middle pregnancg (13-27w). were selected who suffered from threatened abortion. They were divided into two groups. 126 cases in study group at random. Which had been treated continually by the preventing miscarriage therapg including antibiotics for three days. 130 cases in control group. Which were treated by the preventing miscarriage therapg without antibiotics. WBC and CRP in the blood were examined before treatment and after treatment three days respe otivelg. Results (1) In study group There were striking difference between before and after treatment in changes of CRP (P>0.05) while indapparent difference were found in control group .There were no significant difference between before and after in changes of WBC and RCP (P>0.05) (2)101 cases (80.2%) in study group and 81 cases (63.1%) in control group were cured successfully. There were great difference between two groups compared in the Success rate (P>0.05). Conclusions Using antibiotics in the preventing theory for the late threatened abortion brought out conspicuous effects. CRP in serum benefit the prognosis of pregnancg edding.