陕西地区格林-巴利综合征发病的季节性研究

Seasonal variation of Guillain－ Barre syndrome in Shaanxi province

目的探讨陕西地区格林－巴利综合征 (Guillain－ Barre， GB）发病的季节性特点。方法回顾性分析 1980～ 1999年我院诊断的 376例 GB病人的的临床资料，应用圆形分布法和卡方检验进行统计学处理。结果陕西地区 GB发病具有明显的季节性特点，圆形分布集中值 r = 0.305， P< 0.001。发病高峰日为 8月 31日，高峰期为 6月 2日～ 11月 27日。卡方检验表明 GB发病的季节性规律与年龄没有关系。结论陕西地区 GB主要集中在夏秋季节发病。

Objective To study the seasonal variation of Guillain－ Barré syndrome (GBS) incidence .Method The clinical data of 376 cases with GBS from 1980 to 1999 occurring in Shaanxi province were analysed with circular distribution method andχ 2test. Result There is a clearly seasonal preponderance in GBS incidence in Shannxi province. The date of the highest peak of GBS incidence was around August 31th. The peak period began from June 2th to November 27th.χ 2 test revealed that seasonal variation of GBS incidence did not concern with age.Conclusion GBS in Shaanxi province mainly occurred in summer and autumn.