彩色多普勒超声对肢端硬皮病外治法的研究

The study of exterior treatment to patients with acrosderoderma by color Doppler ultrasonography

目的 应用彩色多普勒血流显像(CDFI)观察温度对肢端硬皮病外周血管血液动力学指标的影响,说明中医外治法的作用。方法 应用9MHz彩色超声观测肢端硬皮病患者桡动脉(n=30)于温热刺激前后血管内径、血流参数和阻力指数的变化,与正常人作对照。同时计算血管内径扩张和血流速度增加的百分比。结果 温热刺激正常人与肢端硬皮病患者桡动脉血管扩张、血液流速增加、阻力指数下降,各组间比较有非常显著性差异(P<0.01);肢端硬皮病患者桡动脉扩张程度、收缩期血液流动速度增加的百分比与正常人比较有非常显著性差异(P<0.01)。结论 温热刺激是检验血管内皮依赖性舒张功能的一种方法,同时是中医活血化瘀、温经通络、见效快的一种外治法。

Objective To observe the effect of temperature to peripheral vascular kinetics indexes of patients with acroscleroderma by color Doppler flow imaging (CDFI) and explain the function of Chinese medical exterior treatment . Methods The changes of blood vessels bore, blood stream parametes and resistent indexes were examined before and after lukewarm stimulations from patients with acroscleroderma at normal control group by color Doppler ul-trasonography at 9MHz transducer, and the growth rates of blood vessels' bore and blood stream velocity were calculated. Results Radial arterias were expanded, blood stream velocity was increased, and resistent indexes were descended in both patients and control group after lukewarm stimulations. But the differences were remarkable ( P < 0.01) comparing with control group. The degree of radial arterias expansion and the growth rates of blood stream velocity in systole were lower than normal control group . The differences were remarkable too ( P <0.01). Conclusion Lukewarm stimulation is a kind of method to examine the function of endothelium and a kind of effective Chinese medical exterior treatment method to invigorate blood circulation ization silt and warm but held openly in place with a net.