糖尿病合并冠心病患者经皮冠状动脉腔内血管成形术术后即时疗效观察

Immediate curative effectiveness of PTCA in diabetic patients with coronary heart disease:an observation

目的 对糖尿病 (DM )合并冠心病和非DM冠心病患者的冠状动脉造影及冠状动脉腔内血管成形术 (PTCA)作对比研究。方法 从 2 0 0 0年 5月至 2 0 0 2年 1月对 2 4 3例冠心病患者进行经皮冠状动脉腔内血管成形术 (PTCA) ,其中DM患者 30例 ,非DM患者 2 13例 ,PTCA术后即刻行冠状动脉造影观察疗效。结果 DM组冠状动脉狭窄程度重 ,复杂病变多 ,多支病变比率高 (43.3% )、非DM组多支病变比率为 16 .9% ,两组有显著性差异 (P <0 .0 1) ;PTCA术后 :DM组术前平均狭窄 (91.3± 12 .6 ) % ,显著高于非DM组 (86 .7± 5 .7) % (P <0 .0 1) ,术后残余狭窄DM组为 (15 .7± 9.7) % ,非DM组为 (7.3± 3.1) % ,临床成功率无显著性差异 ,分别为 92 .3%与94 .2 %。结论 PTCA是合并DM的冠心病患者冠状动脉即时再通有效、安全的方法。

Objective To observe the immediate curative effectiveness of percutaneous transluminal coronary angioplasty(PTCA) in diabetic (DM) patients with coronary heart disease. Methods The results in 30 patients with DM receiving PTCA were compared with that in 213 patients without DM receiving PTCA from May. 2000 to Jan. 2002. Results More patients with DM suffered from severe coronary stenosis than those without DM. There were significant differences between the two groups: multi vessel disease was found in 43.3% of patients in DM group vs 16.9 % of patients in group without DM(P<0.01). The degree of vessel stenosis in the two groups had significant difference before and after PTCA,(91.3±12.6)% vs (86.7±5.7)% and (15.7±9.7)% vs(7.3± 3.1 )%, respectively (P< 0.01 ). Conclusions Patients with DM have more severe coronary artery disease and PTCA is an effective therapeutic method for diabetic patients with coronary heart disease.