期刊文献+

影响骨肉瘤化疗疗效因素的研究进展

Research progress in the effective factors influencing chemotherapy for osteosarcoma
下载PDF
导出
摘要 骨肉瘤是临床上最常见的一种原发恶性骨肿瘤,好发于青少年,在应用化疗之前,预后极差,5年生存率不及20%.70年代以来随着辅助化疗和新辅助化疗概念的提出及临床应用,不仅将5年生存率提高至60%~70%,而且对80%以上的患者可以保存肢体,因此正规的化疗成为骨肉瘤治疗中不可缺少的重要驵成部分[1].随着各种化疗方案临床应用病例数的增加,及相关基础理论研究的不断深入,发现许多因素均影响骨肉瘤的化疗疗效.现就有关因素的研究进展作一综述.
出处 《中国骨肿瘤骨病》 2002年第4期206-208,共3页 Chinse Journal Of Bone Tumor And Bone Disease
  • 相关文献

参考文献27

  • 1于秀淳,刘晓平,李开华.恶性骨肿瘤保肢技术的最新进展[J].中华骨科杂志,2000,20(7):424-427. 被引量:28
  • 2[2]Bramwell VH. The role of chemotherapy in the management of non-metastatic operable extremity osteosarcoma. Semin Oncol, 1997,24: 561-571.
  • 3[3]Marina NM, Poquette CA, Cain AM, et al. Comparative renal tubular toxicity of chemotherapy regimens including ifosfamide in patients with newly diagnosed sarcomas. J Pediatr Hematol Oncol,2000,22:112 ~ 118.
  • 4[4]Ferrari S, Mercuri M. Picci P, et al. Nonmetastatic osteosarcoma of the extremity: results of a neoadjuvant chemotherapy protocol(IOR/OS-3) with high-dose methotrexate, intraarterial or intravenous cisplatin, doxorubicin,and salvage chemotherapy based on histologic tumor response. Tumori,1999,85:458-464.
  • 5杨迪生,范顺武,陶惠民,叶招明,何荣新.骨肉瘤辅助化疗方案的中、远期疗效观察[J].中华骨科杂志,2000,20(1):35-39. 被引量:27
  • 6[6]Robert LS, Alan WC, Jan W, et al. Randomised trial of two regimens of chemotherapy in operable osteosarcoma: a study of the European Osteosarcoma Intergroup. The Lancet, 1997,350:911-917.
  • 7[7]Voute PA, Souhami RL, Nooij M, et al: A phase study of cisplatin,ifosfamid and doxorubicin in operable primary, axial skeletal and metastatic osteosarcoma, European Osteosarcoma Intergroup ( EOI). Ann Oncol,1999,10:1211-1218.
  • 8[8]Kubo T,Sugita T, Shimose S, et al. Targeted delivery of anticancer drugs with intravenously administered magnetic liposome in osteosarcoma-bearing hamsters. Int J Oncol,2000,17:309 ~ 315.
  • 9[9]Rha SY, Chung HC, Gong SJ, et al. Combined pre-operative chemotherapy with intra-arterial cisplatin and continuous intravenous adriamycin for high grade osteosarcoma. Oncol Rep, 1999,6:631-637.
  • 10[10]Tsuchiya H, Morinaga T, Sumiya H, et al. Effect of myocutaneous inflammatory changes caused by intra-arterial chemotherapy on the outcome of patients who undergo limb-saving surgery. Cancer, 2001,91:2447-2453.

二级参考文献7

共引文献53

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部