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动物水泡性口炎病毒的抗原性 被引量：3

Antigencity of Vesicular Stomatitis Virus in Animals
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摘要 动物水泡性口炎病毒(VSV)引起动物水泡性疾病。VSV有两个主要抗原群是核酸蛋白和G蛋白抗原。G蛋白因为能产生中和性抗体被认为是在发动抑制病毒感染方面起主要作用。已经证实VSV 的New Jersey 株中产生独立的中和性单克隆抗体的抗原决定蔟分布在G 蛋白的193～289氨基酸之间。 Vesicular Stomatitis is a disease of livestock caused by vesicular stomatitis virus. VS virus has two major a ntigens:agroup-specific nucleocapsid antigen and a type-specific glycoprotein antigen. VSV G protein are believed to play critical roles promoting resistance to infection after convalescence from infection or vaccination with G protein. binding sites of four independent neutralizing monoclonal antibodies have been mapped to a region between amino acids 193 and 289 of the G protein of the VSV New Jersey.
作者 周学章 高丰 赵文斌
机构地区 中国人民解放军军需大学军事兽医系 军需大学中心实验室
出处 《黑龙江八一农垦大学学报》 2003年第2期68-72,共5页 journal of heilongjiang bayi agricultural university
关键词 水泡性口炎病毒 抗原性 糖蛋白 vesicular stomatitis virus antigencity glycoprotein
分类号 S852.65 [农业科学—基础兽医学]
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参考文献34

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共引文献1

同被引文献23

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黑龙江八一农垦大学学报
2003年 第2期

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