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新疆紫草中抗生育化学成分(英文) 被引量:13

A CONTRACEPTIVE CONSTITUENT FROM ARNEBIA EUCHROMA(ROYLE)JOHNST
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摘要 从新疆紫草 (Arnebiaeuchroma(Royle)Johnst.)的根部分得四种酚类化合物 ,经波谱分析 ,确定为rabdosiin二钾盐 (dipotassiumrabdosiin 1) ,迷迭香酸钾盐 (potassiumrosmarinate 2 ) ,迷迭香酸钠盐(sodiumrosmarinate 3) ,阿魏酸钠盐 (sodiumferulate 4)。其中rabdosiin二钾盐具有显著的抗生育活性 ,而迷迭香酸钾盐。 From the roots of Arnebia euchroma(Royle) Johnst., dipotassium rabdosiin 1, potassium rosmarinate 2, sodium rosmarinate 3 and sodium ferulate 4, were isolated by means of reversed phase chromatography. Their structures were identified by spectral analyses (UV, IR, MS, 1H NMR, 13C NMR). Compound 1 exhibited conspicuous contraceptive effect. Compound 2,3 and 4 were discovered in the roots of A.euchroma firstly.
出处 《天然产物研究与开发》 CAS CSCD 2002年第1期1-4,共4页 Natural Product Research and Development
基金 NationalLaboratoryofDrugsandDevicesforFamilyPlanning
关键词 新疆紫草 rabdosiin二钾盐 抗生育活性 Arnebia euchroma(Royle) Johnst. dipotassium rabdosiin contraceptive effect
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  • 1[1]Liu F, et al. Terminating the early pregnancy activity of Arnebia euchroma in mice and rabbits. Journal of Xinjiang Medical University, 1982,5:199
  • 2[2]Isao A, et al. A tetrameric derivative of caffeic acid from Rabdosia japonica. Ph ytochemistry , 1989,28 (9): 2447
  • 3[3]Charles JK, et al. Carbon-13 nuclear magnetic resonance of lithospermic and rosmarinic acids J Org Chem, 1975, 40(12): 1804
  • 4[4]Charles JK, et al. isoiation and. structure determination of lithospermic acid. J Org Chem, 1976, 41(3): 449

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