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凋亡与自身免疫性疾病的临床联系

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摘要 凋亡是以形态学和生物化学的一系列改变为特征的,这些变化包括细胞内蛋白水解酶对细胞核以及细胞浆中底物的分解等.凋亡可能是由于生存信号的缺乏所引起的,也可能由于各种损伤刺激而被激活,如缺氧、反应性氧自由基拉动、补体激活、一氧化氮以及肿瘤坏死因子、CD95细胞表面终末的Fas受体配体等细胞因子.
作者 罗莉漫 余健
出处 《华南国防医学杂志》 CAS 2003年第4期23-25,共3页 Military Medical Journal of South China
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