摘要
目的 探讨腹腔洗液细胞学检查在评价子宫内膜癌患者预后中的价值。方法 对1992年1月～2000年1月我院收治临床分期Ⅰ-Ⅱ期的113例子宫内膜癌患者进行回顾分析及随访。结果 113例子宫内膜癌患者中,腹腔洗液细胞学检查阳性者23例(20.4％),其中4例(17.4％)死于术后复发;90例阴性的患者中,13例(12.56％)死于术后复发,Cox回归分析显示腹腔洗液细胞学检查结果与子宫内膜癌预后相关无显著性(P=0.9516);23例阳性患者中,6例(26％)为不良病理类型,9例(39％)有深肌层浸润,5例(21.7％)宫颈受累,5例(21.7％)有淋巴结转移,Logistic回归多因素分析表明与腹腔洗液细胞学检查阳性有显著相关(P<0.05)。结论 腹腔洗液细胞学检查不能独立作为评价子宫内膜癌患者预后的指标。与腹腔洗液细胞学检查阳性有关的高危因素有不良病理类型、深肌层浸润、宫颈受累和淋巴结转移。
Objective To evaluate the prognostic significance of peritoneal cytology in endometrial carcinoma. Method Clinical and follow- up data were analyzed retrospectively in 113 cases with endometrial carcinoma clinical stage I and Ⅱ , undergoing surgical operations in our hospital from 1992 to 2000. Results There were 23 (20.4%) cases with positive peritoneal cytology (PPG) in the total 113 patients. Four of the 23 positive cases (17.4%) died of relapse after operation, 13 of 90 (12.56%) in negative group died of rekpse instead. Peritoneal cytology had no significant correktion with the prognosis of endometrial carcinoma (P = 0.9516) . In 23 PPG cases, 6 (16%) had poor pathological types; 9 (39%) with deep muscle infiltration, 5 (21.7%) got cervical involvement, 5 (21.7%) with lymph node metastasis. Cox regression analysis revealed that they had significant correlation with PPC.Conclusions Peritoneal cytology can not be regarded as an independent criteria in evaluating the prognosis of endometrial carcinoma. The high risk factors related to PPC include poor pathological types, deep muscle infiltration, cervical involvement and lymph nodes metastasis.
出处
《中国妇产科临床杂志》
2001年第3期156-158,161,共4页
Chinese Journal of Clinical Obstetrics and Gynecology
