摘要
目的:研究复方茵陈片对HBsAg和HBeAg表达的抑制作用。方法:分别以不同浓度含药培养基培养2.2.15细胞,运用放射性免疫测定方法检测乙型肝炎表面抗原和e抗原。结果:复方茵陈片药液最大无毒浓度为600 g·mL-1。在此浓度基础上以培养基递减稀释药液,给药组的2.2.15细胞HBsAg和HBeAg cpm值明显低于细胞对照组。结论:复方茵陈片可以抑制HBV的复制和表达。
Objective: To study the inhibitory effect of FFYC tablets (FFYC) on expression of HBeAg and HBsAg. Methods: The 2.2.15 cell line was cultured with cell cultured medium including different concentration of FFYC. By means of radioimmunoassay, the hepatitis B surface antigen ( HBsAg) and hepatitis B e antigen (HBeAg) were examined. Results: The max cytotoxicity concentration of FFYC was 600g/mL. Based on this concentration, FFYC was diluted and was added in cell culture medium. The results showed that HBeAg, HBsAg values of 2.2.15 cells treated by FFYC were lower than those in the control. Conclusion: FFYC could inhibit HBV replication and expression.
出处
《抗感染药学》
2004年第3期127-128,共2页
Anti-infection Pharmacy
