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他汀类药物降低LDL-C目标分析

Analysis of the target for lowering LDL-C by statins
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摘要 他汀类药物降低低密度脂蛋白胆固醇(LDL-C)的目标值应该是多少仍存在争议,部分临床研究显示,强力降低LDL-C不能进一步减少患者临床终点发生率,但包括流行病学和他汀类调脂的大多数研究显示,他汀类使LDL-C下降到现有调脂指南标准以下能使患者进一步受益,降的越低,获益越大。因此,提倡在临床实践中将LDL-C降到现有指南推荐水平以下,对于高危患者降的越低越好。
作者 徐泽昌
出处 《中国药物应用与监测》 CAS 2004年第3期16-19,共4页 Chinese Journal of Drug Application and Monitoring
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  • 1[1]Brown WV.What are the priorities for managing cholesterol effectively[J].Am J Cardiol,2001,88 ( suppl ) :21F.
  • 2[2]The Expert Panel.Executive summary of the third report of the national cholesterol education program expert panel on detection,evaluation,and treatment of high blood cholesterol in adults ( Adult Treatment Panel Ⅲ ) [J].JAMA,2001,285:2486.
  • 3[3]The Expert Panel. Report of the national cholesterol education program expert panel on detection, evaluation, and treatment of high blood cholesterol in Adults[J].Arch Intern Med, 1988,148:36.
  • 4[4]Ansell BJ,Watson KE, Fogelman AM.An evidence-based assessment of the NCEP ATP- Ⅱ guidelines[J].JAMA, 1999,282:2051.
  • 5方圻,王钟林,宁田海,邵耕,陈在嘉,陆宗良,李健斋,林传骧,周北凡,诸骏仁,诸永康,陶萍,陶寿淇,龚兰生,顾复生,游凯,戴玉华.血脂异常防治建议[J].中华心血管病杂志,1997,25(3):169-175. 被引量:3067
  • 6[6]Sacks Fm,Pfeffer MA,Moye LA,et al for the cholesterol and recurrent events trial investigators.The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels[J].N Engl J Med,1996,335:1001.
  • 7[7]The long-term intervention with pravastatin in ischaemic disease (LIPID)study group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels[J].N Engl J Med, 1998,339:1349.
  • 8[8]Pfeffer MA,Sacks Fm,Moye LA,et al. Influence of baseline lipids on effectiveness of pravastatin in the CARE trial[J].J Am Coll Cardiol, 1999,33:125.
  • 9[9]Castelli WP.Making practical sense of clinical trial data in decreasing cardiovascular risk[J].Am J Cardiol,2001,88 (suppl):16F.
  • 10[10]Verschuren WM,Jacobs DR,Bloembery BP,et al. Serum total cholesterol and long-term coronary heart disease mortality in different cultures:twenty-five-year follow-up of the seven countries study[J].JAMA, 1995,274:131.

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