绵马贯众、紫萁和单芽狗脊贯众饮片抗菌及凝血试验对比研究

Comparison research of the herb processed products of Osmunda japonica, Woodwardia unigenmata and Dryopteris crassirhizoma

目的:为紫萁、单芽狗脊贯众寻找临床用药依据。方法:以对9个菌种的抑菌活性和凝血时间为指标,对紫萁、单芽狗脊贯众与绵马贯众的饮片进行比较研究。结果:三种药材的生品均有抑菌活性,对不同菌种其抑菌活性各有不同。三种药材的炭品均有凝血作用,以单芽狗脊贯众作用最强,绵马贯众次之,紫萁更次之。抑菌活性生品明显强于炭品,凝血作用炭品明显强于生品。结论:为市场主流品种紫萁、单芽狗脊贯众找到了临床用药依据,证实了生品长于驱虫、清热解毒,炭品长于止血的传统炮制理论是科学的。

Objective:The goal is to find out the basis of the clinical use of Osmunda japonica and Woodwardia unigenmata. Method: Regarding antibacterial activity and coagulation time (CT)as the index sign,the herb processed products of Osmunda japonica,Woodwardia unigenmata and Dryopteris crassirhizoma were compared. Result:The results showed that these three kinds of medicines all have antibacterial activity,despite their different effects on different germs.They all can shorten the coagulation time,and Woodw.ardia unigenmata is the strongest, Dryopteris crassirhizoma weaker, Osmunda japonica weakest.The results also told us that antibacterial activity of the raw products was obviously stronger than that of the charred products. However, the action of the hemostasis of the charred products is significantly stronger than that of the raw products. Conclusion: Thus we can find out the basis of the clinical use of Osmunda japonica and Woodwardia unigenmata The research has verified the traditional herb processing theory that the raw products are better than the charred products at expelling worms as well as clearing away heat-toxin, and the charred products better at stopping bleeding.