霍奇金淋巴瘤的受累野照射

Involved field radiotherapy for Hodgkin's lymphoma

最近几十年,放射治疗在霍奇金淋巴瘤治疗中的作用发生了很大的变化。在20世纪60-70年代,扩大野照射可以有效地治愈大部分早期和中期HL。最近10年,化疗加受累野照射已成为Ⅰ-Ⅱ期HL的主要治疗手段,对于Ⅲ-Ⅳ期化疗后的患者,受累野照射应用于大肿块或残存病灶。本文描述受累野的定义、设计和常见受侵部位的射野边界。

During the last decades, the role of radiotherapy in the treatment of Hodgkin's lymphoma had changed dramatically. In the 1960s and 1970s, most patients with early and intermediate stage Hodgkin's lymphoma were successfully cured with extended field radiotherapy. In recent 10 years, chemotherapy followed by involved field radiation has become a primary therapy for stage Ⅰ and Ⅱ HL, In patients with stage Ⅲ-Ⅳ disease , involved field radiotherapy was applied to bulky or residual lesions after combination chemotherapy. This article addresses the delineation of involved field, design questions and offer field borders for common involved sites.