上海市社区癌症患者抑郁状况初步研究

Initial study of depression of cancer patients in community of Shanghai

目的 探讨社区癌症患者发生抑郁的相关因素 ,以提高临床工作者对癌症患者抑郁的认识 ,为在社区中开展癌症患者抑郁的防治提供理论依据。方法 选择上海市社区癌症患者共计2 5 2 5例 ,调查方法包括自评和访谈 ,采用国内外通用的癌症患者生活质量自评量表FACT -G ,抑郁自评量表Zung以及有关癌症患者疾病和社会信息的一般状况登记表。采用多元Logistic回归分析方法处理数据。结果 本组患者抑郁发生率为 2 3 3% ,有 5种因素与社区中的癌症患者抑郁发生密切相关 ,依次为 :KPS评分、受教育程度、疼痛状况、收入和年龄 ,其相关系数和显著性检验分别为 - 0 0 4 4、 0 0 0 0 ;0 189、 0 0 0 0 ;0 72 0、 0 0 0 0 ;0 2 17、 0 0 0 0 ;0 0 12、 0 0 0 3。结论 KPS评分下降、受教育程度低、出现癌痛症状、收入状况差和年龄大的患者 ,其抑郁的发生率也相应高。

Objective In this study,we want to study the related factors which may affect depression of cancer patients and to improve the recognition of clinical workers for that of cancer patients.Then we hope to provide supports to evolve prevention and cure of depression of cancer in community of Shanghai.Methods 2525 cancer patients who live in community of Shanghai were enrolled.The methods include self-comment and being visited.We adopt the FACT-G,which has been applied widely in cancer patients QOL for both foreigners and Chinese people,ZUNG and collect the information about disease and common society characteristic of patients.All the data were analysised by multinomial logistic regression methods.Results The depression rate is 23.3% in our study.There are 5 factors which have close relationship with depression of cancer patients.They are KPS,education,pain.income and age.coefficient regresion and P valure are -0.044,0.000;0.189,0.000;0.720,0.000;0.217,0.000;0.012,0.003 respeetively.Conclusion Patients who have a poor KPS.low education level,pain,poor income and old age will easily to have depression.