异常胰胆管连接与先天性胆管囊肿的关系研究

A study on etiologic relationship between anomalous pancreaticobiliary ductal union and congenital choledochal cyst

目的 研究异常胰胆管连接 (APBDU)在先天性胆管囊肿病因学中的作用、基本特征及可能的病理学机理。材料与方法 对 2 35 4例ERCP资料进行回顾性分析 ,共诊断出APBDU118例 (5 .0 % ) ,其中有完整临床资料者 79例 ,合并先天性胆管囊肿 2 1例。将此 2 1例临床和ERCP表现 ,分别与 9例同期正常胰胆管连接 (NPBDU)所合并的先天性胆管囊肿进行比较。结果 先天性胆管囊肿在APBDU中的发生率明显增高 (2 6 .6 % )。其中肝外胆管囊状扩张的APBDU(9/ 11)多在此囊状扩张的胆总管下段见明显的缩窄段 (占 81.8% )。结论 APBDU与先天性胆管囊肿有明显的病因学联系。

Purpose In order to clarify the role played by abnormalous pancreaticobiliary ductal union(APBDU)in the etilogy,clinical characteristics and pathogenesis of congenital choledochal cyst.Materials and methods The ERCP materials of 2354 cases were reviewed,APBDU was found in 118 patients(5.0%) of whom 79 patients had complete clinical data and were categorized as group A.59 cases with surgically and/or pathologically confirmed pancreaticobiliary disease but normal pancreaticobiliary ductal union(NPBDU)were selected from the previous ERCP materials and categorized as group N.[WT5”HZ]Results The incidence of congenital choledochal cyst was higher in group A than in group N.There was a distinct narrow segment just below the cystically dilated bile duct in 9/11 patients of group A.Conclusion APBDU contributed significantly to the etiology of congenital choledochal cyst.