恶性肿瘤特异性生长因子对肺癌的诊断价值

Clinical Value of Serum TSGF Examination to Lung Cancer

目的 评价血清恶性肿瘤特异性生长因子 (TSGF)在肺癌诊断中的意义。方法 检测 6 4例临床诊断为肺癌 ,36例肺良性病变 (BPD)患者血清TSGF ,并与 42例正常人对照。结果 肺癌组TSGF为 (81 2 8± 14.5 7)U/ml,阳性率 81 2 % ,与BPD组及正常对照组有显著性差异 ,P <0 .0 1;BPD组治疗前与正常对照组有显著性差异 ,P <0 .0 1;BPD组抗炎治疗 2周后与正常对照组无显著性差异 ,P >0 .0 5。结论 TSGF作为新型的肿瘤标志物对肺癌的诊断具有一定价值。

Objective To evaluate the clinical value of serum tumor specific growth factor(TSGF)examination to lung cancer Method Examine the serum TSGF OF 64 Patients diagnosed clinically as lung cancer, 36 Benign Pulmonary Disease(BPD)patients, and 42 normal people(as control) Result The mean serum TSGF in lung cancer group was 81.28±14.57 μ/ml(the positive rate was 81.20%), which was significantly high compared with that in BPD group or in control group ( P <0.01) There was marked difference in BPD group after treatment for two weeks and before treatment, but no marked difference in control group ( P >0.05) Conclusion As a new carcinoma symbol, TSGF has some value to Lung cancer diagnosis