选择性食管动脉灌注化疗治疗68例中晚期中下段食管癌

68 Cases with Advanced Carcinoma in Medial or Lower Esophagus Treated by Selective Esophageal Arterial Infusion

目的 观察用选择性动脉灌注化疗治疗中晚期中下段食管癌的疗效 ,了解临床分期和影像分型对疗效的影响。方法 对 6 8例中晚期中下段食管癌行选择性食管动脉灌注化疗 ,并随访 6个月。结果 患者的总缓解率及中、晚期缓解率分别为 48 5 % ,6 1 9%和 2 6 9% ,中晚期疗效相差显著 (P <0 .0 5 )。影像Ⅰ Ⅳ型的缓解率分别为 42 3 % ,5 2 0 % ,6 4 3 %及 0 % ,型间相差不显著 (P >0 .0 5 )。结论 动脉灌注化疗对中晚期中下段食管癌疗效可靠 ;临床分期可以直接影响患者的疗效 ;但影像分型对疗效无影响。

Objective To observe the response of advanced carcinoma in medial or lower esophagus treated by selective arterial infusion and to analyse the treatment influence from clinical stage and imageological classification Method 68 patients with advanced carcinoma in their medial or lower esophagi were treated by selective esophageal arterial infusion and were followed up for six months Result The total, the TNMⅡ、Ⅲ stage teams' and the TNMⅣ stage team's remission rates were 48.5%, 61.9%, and 26.9% repectively There was a significant difference between the two teams' responses ( P <0.05) Imageological Ⅰ Ⅳ types' remission rates were 42.3%, 52.0%, 64.3% and 0% respectively There was no difference between every two types ( P >0.05%) Conclusion (1) Selcctive arterial infusion was an effective therapy to treat advanced carcinoma in medial or lower esophagus (2) Clinical stages might directly influence treatment effect (3) Imageological classification might have nothing to do with treatment effect