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Ki-67检测及DNA倍体分析与乳腺癌淋巴转移倾向的研究 被引量：2

Kl-67 Examination and DNA Ploidy Analysis on Breast Cancer to Evaluate the Metastases in Axillary Lymph Nodes
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摘要 目的:探讨Ki-67基因在乳腺癌组织的表达及DNA倍体与其淋巴转移倾向的关系.方法:采用流式细胞技术对72例乳腺癌组织新鲜标本进行Ki-67表达及肿瘤细胞DNA倍体含量检测的研究.结果:Ki-67表达与乳腺癌肿瘤大小、病理类型和ER无关.乳腺癌腋淋巴转移阳性组DNA异倍体高于无淋巴转移组(P＜0.05),Ki+67在腋淋巴转移阳性组高表达.阳性组表达12.6l±6.23;阴性组表达7.6l±3.85(P＜0.05).结论:Ki-67表达及DNA倍体可作为判断乳腺癌具有转移倾向的临床参考指标.肿瘤防治杂志,2001,8(特)
作者 付荣湛 阮长乐 于学智 曹莉莉 刘群 顾禾
机构地区 山东省千佛山医院普外中心山东济南
出处 《中华肿瘤防治杂志》 CAS 2001年第z1期240-242,共3页 Chinese Journal of Cancer Prevention and Treatment
关键词 乳腺癌 KI-67 DNA倍体 淋巴转移
分类号 R737.9 [医药卫生—肿瘤]
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参考文献7

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同被引文献52

  • 1杨祖贻,罗洁,宋秀云,陈明辉.肺癌、肝癌、大肠癌、乳腺癌患者免疫功能的临床研究[J].四川医学,2005,26(7):754-755. 被引量：6
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  • 7Spaggiari GM,Capobianco A,Abdelrazik H,et al. Mesenchymal stem cells inhibit natural killer-cell proliferation,cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2[J]. Blood,2008,111(3) : 1327-1333.
  • 8Traggiai E,Volpi S,Schena F,et al. Bone marrow-derived mesenchymal stem cells induce both polyclonal expansion and differentiation of B ceils isolated from healthy donors and systemic lupus erythematosus patients[J]. Stem Cells,2008,26(2):562-569.
  • 9Guo C,Chu X,Shi Y,et al. Correction of Thl dominant cytokine profiles by high-dose dexamethasone in patients with chronic diopathic throm-bocytopenic purpura[J]. J Clin Immunol,2007, 27(6):557-562.
  • 10Albers Andreas E,Schaefer Carsten,Visus Carmen,et al. Spontaneous apoptosis of tumor-specific tetramer CD8T lymphecytes in the peripheral circulation of patients with head and neck cancer[J]. Head & Neck,2009,31(6):773-781.

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中华肿瘤防治杂志
2001年 第z1期

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