超声雾化吸入与氧气雾化吸入对气道湿化的效果研究

Comparison study on effect of ultrasonic nebulizer and oxygen nebulizer in airway humidifying

目的探讨超声雾化吸入与氧气雾化吸入对气道湿化的临床效果。方法选普通外科腹部手术患者40例,随机分成A组和B组各20例,A组进行超声雾化吸入,B组进行氧气雾化吸入进行气道湿化,稀释痰液排痰,2组患者进行雾化吸入前和雾化吸入15 min后观察患者血氧饱和度、呼吸、心率、血压的变化以及痰液粘稠度等指标。结果2组雾化吸入前后患者血压、血氧饱和度以及痰液粘稠度之间差异无统计学意义(P>0.05)。A组患者雾化吸入后呼吸、心率均加快,易发生刺激性呛咳反应。2例患者有轻微气喘,与雾化前差异有统计学意义(P<0.05)。B组患者雾化吸入前后呼吸、心率变化差异无统计学意义。结论氧气雾化吸入进行气道湿化,有雾化药液浓度高,颗粒小,对生命体征干扰小,排痰效果好,不易发生刺激性呛咳反应,操作简便等优点,易于被患者接受。

Objective To compare the effect of ultrasonic nebulizer and oxygen nebulizer in airway humidifying.Methods 40 patients who received abdominal operation were divided into two groups: group A(n=20) and group B(n=20).The patients in group A were given ultrasonic nebulizer and those in group B were given oxygen nebulizer and airway humidification.SpO_2,respiration,heart rate,blood pressure and the viscosity of sputum of the patients in two groups were observed before and after airway humidifying.Results In two groups,there were no significant differences in blood pressure and SpO_2 and the vislosity of sputum before and after airway humidifying(P>0.05).However,the patients in group A had higher frequency of respiration and heart rate after the airway humidification,and 2 patients suffered wheeze,and the differences were significant before and after airway humidifying(P<(0.05)).In patients in group B,there were no significant differences in the frequency respiration and heart rate before and after airway humidifying.Conclusions Oxygen nebulizer used in airway humidifying has the advantages such as high concentration of nebular liquid,small drug units,less disturbance in vital sign,good effect of expectoration,less irritative cough and simple operation,so it is easy to be acceptable by the patients.