摘要
目的 了解红霉素在手术并发急性肺损伤 (ALI)中的治疗作用。方法 采用犬在腹部手术中人为静脉推注油酸制造ALI模型 ,观察红霉素对损伤肺嗜中性粒细胞聚集的影响及对氧自由基的干预作用。结果 红霉素可有效地抑制嗜中性粒细胞在肺内的聚集 ,减少氧自由基的产生 ,减轻肺局部损伤的程度。
Objective To explore the treatment effect of erythromycin in operation with acute lung injury.Methods Intravenous injection of oleic acid was used to make acute lung injury models during abdomen operation in dogs.The effect of erythromycin on the collection of neutrophil and oxygen free radical injured lung was observed.Results Erythromycin can repress collection of neutrophil,reduce oxgyen free radical and lighten lung injury.Conclusion Erythromycin is a reliable drug in preventing acute lung injury in...
