福辛普利与卡维地洛联合治疗充血性心力衰竭临床观察

Clinical Observation the Effects of Fosinopril Plus Carvedilo in the Treating Patients with Congestive Heart Failure

目的:观察福辛普利和卡维地洛联合治疗慢性充血性心力衰竭(CHF)的临床疗效。方法:60例CHF患者(NYHA心功能Ⅱ-Ⅳ级)在常规治疗的基础上随机分成2组,治疗组口服福辛普利和卡维地洛,对照组口服福辛普利,疗程4个月。结果:治疗组和对照组患者心功能及生活质量均得到改善,静息心率均降低,左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)缩小,左室射血分数(LVEF)均得到提高,但治疗组较对照组明显,两组有显著性差异(P<0.05)。结论:福辛普利和卡维地洛联合治疗CHF可明显改善心功能,减慢心率,降低血压,缩小LVESD、LVEDD,提高LVEF。

Objective To observation the effects of fosinopril plus carvedilo in the treating patients with congestive heart failure(CHF).Methods Sixty patients with CHF(NYHA class II-IV) were divided randomly into two groups in addition to routine therapy.Treatment group was given fosinopril and carvedilo.Contral group was given fosinopril.Both groups were treated for 4 months.Results Heart function improved,the heart slowed,and LVESD,LVEDD decreased,the LVEF increased after treatment in both groups,especially in trea...