早期机械通气在重型颅脑损伤中的临床应用价值

The Clinical Application Value of Early Mechanical Ventilation on Severe Craniocerebral Injuries

目的:探讨早期机械通气在重型颅脑损伤治疗中的临床应用价值。方法:对2003年5月—2008年4月在我院接受机械通气治疗的重型颅脑损伤患者48例的临床资料进行回顾性分析,48例患者中入院时即刻使用机械通气(A组)26例,治疗过程中出现呼吸功能衰竭后才使用机械通气(B组)22例,对两组间机械通气前后呼吸监测指标(PaO2、R、PaCO2、SaO2)变化及预后情况进行对比分析。结果:B组有l8例(占81.82%)出现呼吸功能衰竭并使用呼吸机,两组机械通气前后PaO2、R、PaCO2、SaO2等呼吸监测指标差异有统计学意义(P<0.05);6个月后按GOS预后判断,两组间死亡率无明显差异,但A组预后优于B组(P<0.05)。结论:重型颅脑损伤后早期应用机械通气能较早地改善患者术后的缺氧症状,有助于纠正损伤后低氧血症和意识恢复,减少并发症,提高生存质量。

Objective To probe into the clinical application value of early mechanical ventilation in the treatment of severe craniocerebral injuries.Methods To retrospectively analyze the clinical data of the 48 patients with severe craniocerebral injuries treated with early mechanical ventilation in our hospital during May 2003 and April 2008.26 cases among 48 cases were given mechanical ventilation right after their admission(group A),22 cases received ventilation when they manifested respiratory function failure(gr...