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Design and testing of micro fluidic chemical analysis chip integrated with micro valveless pump

Design and testing of micro fluidic chemical analysis chip integrated with micro valveless pump
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摘要 A new structure and working principle of the chip integrated with micro valveless pump for capillary electrophoresis was proposed in this paper. The micro valveless pump with plane structure has advantages of simple structure, and the process technology is compatible with existing micro chips for capillary electrophoresis. Based upon the mathematical model, simulation study of micro pump was carried out to investigate the influence of structural parameters on flow characteristics, and the performance of the integrated micro pump was also tested with different control parameters. The simulation results agree with the experimental results. Three samples, which are amino acid, fluorescein and buffer solution, have been examined with this chip. The results of the primary experiments showed that the micro valveless pump was promising in the integration and automatization of miniature integrated fluidic systems. A new structure and working principle of the chip integrated with micro valveless pump for capillary electrophoresis was proposed in this paper. The micro valveless pump with plane structure has advantages of simple structure, and the process technology is compatible with existing micro chips for capillary electrophoresis. Based upon the mathematical model, simulation study of micro pump was carried out to investigate the influence of structural parameters on flow characteristics, and the performance of the integrated micro pump was also tested with different control parameters. The simulation results agree with the experimental results. Three samples, which are amino acid, fluorescein and buffer solution, have been examined with this chip. The results of the primary experiments showed that the micro valveless pump was promising in the integration and automatization of miniature integrated fluidic systems.
出处 《Science China(Technological Sciences)》 SCIE EI CAS 2005年第3期326-337,共12页 中国科学(技术科学英文版)
基金 This work was supported by the National Natural Science Foundation of China(Grant Nos.50335010,50175098).
关键词 MEMS micro valveless pump micro fluidic chip CFD capillary electrophoresis. MEMS micro valveless pump micro fluidic chip CFD capillary electrophoresis
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参考文献1

  • 1J. G. Santiago,S. T. Wereley,C. D. Meinhart,D. J. Beebe,R. J. Adrian.A particle image velocimetry system for microfluidics[J].Experiments in Fluids.1998(4)

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