迷迭香酸的提取与分离纯化工艺研究

Study on the extraction and purification of rosmarinic acid from rosemary

研究了超声波辅助热回流法从迷迭香中提取迷迭香酸的工艺条件,结果表明,超声波预处理时间为10min,15%乙醇为溶剂,提取时间为1h,在此条件下迷迭香酸的提取率为94.94%。提取液经膜过滤、X-5大孔树脂分离纯化,得到了含量为96.82%的迷迭香酸产品。

The extraction of rosmarinic acid from rosemary by ultrasonic wave and thermal reflux was studied.The results showed that the optimal extracting technological conditions were as follows:the time of ultrasonic pretreatment for cells broken was 10 min,extraction solvent was 15% alcohol,the extraction time was 1h.Under these conditions,the extracting rate of rosmarinic acid could reach 94.94%.After the processes of membrane filtration,macroporous resin adsorption,ethyl acetate recrystallization,the rosmarinic ...