摘要
橙皮苷与铜配位后往往有着更好的生物活性,有关橙皮苷铜配合物的结晶过程还少见报道。本文采用二次回归正交旋转组合设计法研究了pH值、培养温度、浓缩比例和培养时间等工艺条件对橙皮苷-铜结晶过程的影响。响应面分析结果表明,橙皮苷-铜结晶的最佳工艺条件为:10.7:1、pH值7.13、培养温度28.6℃和培养时间6.4h。回归分析和脊岭分析结果表明,各因素对配合物结晶的影响大小顺序为:pH值>培养温度>浓缩比例>培养时间。
Hesperidin can possess better biological activity after having coordinated with Cu2+,and rare reports can be reached about the crystallization of hesperidin-Cu.The influences of pH value,incubating temperature,concentration ratio and incubating time on the crystallization process were studied in this paper using quadratic regression orthogonal rotating combination design method.Optimum crystallization technological conditions of hesperidin-Cu according to the results of response surface analysis are as foll...
出处
《中国食品添加剂》
CAS
北大核心
2009年第6期154-159,共6页
China Food Additives
基金
广东省科技计划项目(2007B080401010
2008A080403010和2008A080403009)
2008华南理工大学SRP计划项目
关键词
橙皮苷-铜
结晶工艺条件
正交旋转组合设计
hesperidin-Cu
crystallization technological conditions
orthogonal rotating combination design
