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高通量基因分析在乳腺癌中的应用 被引量：2

Application of High-throughput Gene Expression Profiling to Breast Cancer
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摘要 不同亚型的乳腺癌对治疗的敏感性和预后存在较大差异,高通量基因分析技术广泛应用为乳腺癌治疗方案的选择和预测预后提供了新的途径。全文简述Oncotype Dx和MammaPrint等多基因预测系统和其他基因芯片技术在乳腺癌中的应用。
作者 张萍 顾史洋 胡夕春
机构地区 复旦大学附属肿瘤医院
出处 《肿瘤学杂志》 CAS 2009年第9期802-805,共4页 Journal of Chinese Oncology
关键词 基因芯片 乳腺肿瘤 Oncotype DX MammaPrint
分类号 R737.9 [医药卫生—肿瘤]
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参考文献10

  • 1Kapp AV,Jeffrey SS,Langerod A,et al.Discovery and validation of breast cancer subtypes[].BMC Genetics.2007
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  • 3Sorlie T,Perou CM,Tibshirani R,et al.Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications[].Proceedings of the National Academy of Sciences of the United States of America.2001
  • 4Romond E H,Perez E A,Bryant J,et al.Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer[].The New England Journal of Medicine.2005
  • 5Paik S,Shak S,Tang G, et al.A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer[].New England Journal of Homeopathy.2004
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  • 8Ayers M,Symmans WF,Stec J,et al.Gene expression profiles predict complete pathologic response to neoadjuvant paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide chemotherapy in breast cancer[].Journal of Clinical Oncology.2004
  • 9Liedtke C,Mazouni C,Hess KR,et al.Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer[].Journal of Clinical Oncology.2008
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同被引文献16

  • 1郑聪,张国强.长沙市某大学教室内外空气品质调查[J].建筑热能通风空调,2005,24(2):15-18. 被引量：6
  • 2赵彬,陈玖玖,陈曦.室内颗粒浓度影响因素的集总模型分析[J].清华大学学报（自然科学版）,2005,45(12):1589-1591. 被引量：14
  • 3Cuzick J, Sestak I, Raum M, et al. Effect of anastrozole and tamox- ifen as adjuvant treatment for early - stage breast cancer:l 0 - year a- nalysis of the ATAC trial [ J ]. Lancet Oncol, 2010,11 ( 12 ) : 1135 - 1141.
  • 4Chen JG, Zhu J, Park DM, et al. Trends in the incidence of cancer in Qidong, China,1978 -2002[J. Int J Cancer, 2006, 119(6) : 1447 - 1454.
  • 5Yee YK, Gu Q, Hung I, et al. Trend of colorectal cancer in Hong Kong: 1983 2006 [ J]. Gastroenterol Hepatol, 2010, 25 (5) : 923 - 927.
  • 6Perquin M, Oster T, Maul A, et al. The glutathione - related detoxi- fication pathway in the human breast: a highly coordinated system disrupted in the tumour tissues [ J ]. Cancer Lett, 2000, 158 ( 1 ) : 7 -16.
  • 7Coon JS, Marcus E, Gupta-Burt S, et al. Amplification and over- expression of Topoisomerase IlctPredict response to anthracycline - based therapy in locally Advanced breast cancer [ J ]. Clin Cancer Res, 2002, 8(4) : 1061 - 1067.
  • 8Shimizu D, IshikawaT, Ichikawa Y, et al. Current Progress in the prediction of chemo- sensitivity for breast cancer[ J]. Breast Canc- er, 2004, 11 ( 1 ) : 42 - 48.
  • 9贾小宁,张庆芳,陈华春,高鹏.采暖期和非采暖期某高校教室空气质量监测[J].环境与健康杂志,2010,27(9):834-834. 被引量：3
  • 10吴菲,林国桢,张晋昕.我国恶性肿瘤发病现状及趋势[J].中国肿瘤,2012,21(2):81-85. 被引量：373

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肿瘤学杂志
2009年 第9期

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