固定正畸患者龈沟液中P物质表达的研究

Expression of Substance P in gingival crevicular fluid during orthodontic treatment

目的通过对固定正畸患者不同矫治时期的龈沟液(GCF)进行P物质(SP)的含量的测定,来研究固定矫治器对牙周组织的影响。方法随机抽取口腔正畸科门诊牙拥挤错颌患者31例,采用放射免疫技术测量GCF中SP的含量,分析龈沟液的量与SP的含量在矫治过程中的变化关系。结果与矫治前1周比较,矫治过程中GCF的量与SP的含量均有不同程度的上升趋势。结论正畸过程中固定矫治器对牙周组织的健康有影响,SP的检测可用于监测固定正畸过程中患者的牙周健康状况。

Objective: To study the expression of Substance P(SP) in gingival crevicularfluid(GCF) in different stages of orthodontical patients and evaluate the effects of the fixed orthodontic appliances on the the periodontal tissues.Methods: 31 patients with malocclusion were selected in this study.The amount of SP was measured by radioimmunity.Then to analyze the amount change between GCF and SP during the orthetic process.Results: The level of GCF and SP were all increased compared to the period of pre-treatmen.C...