新生儿先天性甲状腺功能低下症的危险因素

Risk factors for congenital hypothyroidism in newborn

新生儿先天性甲状腺功能低下症(CH)的发病率呈上升趋势报道增多,总结分析影响甲状腺发育和甲状腺素合成的危险因素对防治CH很有必要。通过流行病学分析,临床研究及分子生物学的探索,目前影响CH发生的危险因素有家族史、代谢性疾病、摄碘不足或碘暴露、致畸因子和早产等,其发病可能是遗传与环境因素共同作用的结果。

Reports on upward trend in the incidence of congenital hypothyroidism(CH) In newborn are increase.It is necessary to analyze the risk factors that affect the thyroid development and synthesis of thyroid hormones.Through epidemiological analysis,clinical research and molecular biology,currently the risk factors affecting CH include family history,metabolic diseases,inadequate intake of iodine or iodine exposure,teratogenic factors and premature birth etc,it may be the interaction of both genetic and environm...