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Inhibitory Effect of Kangjia Pill(抗甲丸) on Thyrocyte Proliferation in Rat Goiter Model

Inhibitory Effect of Kangjia Pill(抗甲丸) on Thyrocyte Proliferation in Rat Goiter Model
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摘要 Objective:To investigate the inhibitory effects of Kangjia Pill(抗甲丸,KJP)on the cell proliferation in rat goiter model induced by methimazole(MMI).Methods:Fifty-six Wistar rats were randomly divided into four groups:the normal group,MMI model group(MMI),low dose of KJP group(LKJP),and high dose of KJP(HKJP). Except the normal group(20 rats),the other groups(12 rats in each)were given 0.04%(w/v)MMI through the drinking water until the end of the experiment.One week later,the rats in the LKJP and HKJP groups w... Objective:To investigate the inhibitory effects of Kangjia Pill(抗甲丸,KJP)on the cell proliferation in rat goiter model induced by methimazole(MMI).Methods:Fifty-six Wistar rats were randomly divided into four groups:the normal group,MMI model group(MMI),low dose of KJP group(LKJP),and high dose of KJP(HKJP). Except the normal group(20 rats),the other groups(12 rats in each)were given 0.04%(w/v)MMI through the drinking water until the end of the experiment.One week later,the rats in the LKJP and HKJP groups w...
出处 《Chinese Journal of Integrative Medicine》 SCIE CAS 2009年第4期284-288,共5页 中国结合医学杂志(英文版)
基金 Supported by the National Natural Science Foundation of China(No.30672748) the Natural Science Foundation of Shandong Province(No.22003C02) the Shandong Administration of Traditional Chinese Medicine(No.2005-070)
关键词 GOITER Chinese medicine cell proliferation proliferating cell nuclear antigen cyclin D1 goiter Chinese medicine cell proliferation proliferating cell nuclear antigen cyclin D1
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