1125例梅毒分析

Analysis of 1125 Syphilis Cases

目的观察梅毒的流行病学、临床和血清学特征。方法对1125例梅毒患者的临床资料进行综合分析。结果非婚性接触是主要传染来源;一期梅毒129例,以外生殖器硬下疳为主;二期梅毒357例,以掌跖暗红斑、扁平湿疣为主;早期潜伏梅毒178例、晚期潜伏梅毒174例、不能确定病期的潜伏梅毒285例。1125例梅毒患者中107例(9.51%)合并其他性传播感染,绝大多数使用苄星青霉素治疗,青霉素过敏者31例(2.75%)。除一期梅毒外,其余各期梅毒血清学检查(包括快速血浆反应素环状卡片实验、梅毒螺旋体明胶凝结实验、梅毒螺旋体血凝实验、荧光螺旋体抗体吸附实验)敏感性均超过97%。结论潜伏梅毒发病率高,晚期梅毒发病率低,青霉素仍然是治疗梅毒的首选药物。

Objective To summarize the epidemiological,clinical and serological features of syphilis.Method The clinical data of 1 125 patients with syphilis were retrospectively analyzed.Results Non-marital sexual intercourse is the main route of infection.The 129 cases of primary syphilis were featured by extragenital chancres and the 357 cases of secondary syphilis were featured by scaling macules on the palms and soles and condylomata lata.Early latent syphils were detected in 178 cases,late latent syphilis in 174 ...