藏药髯花杜鹃花中化学成分的研究

Studies on chemical constituents of the flowers from Rhododendron anthopogon

目的研究藏药髯花杜鹃Rhododendron anthopogonD.Don花中的化学成分。方法采用95%乙醇提取制备总浸膏,经萃取及柱层析分离,核磁共振鉴定结构。结果分离得14个已知化合物,分别为三油酸甘油酯、3-羟基-3-苯基丙酰胺、齐墩果酸甲酯、熊果酸、2-羟基-4-甲氧基苯酚、5-甲氧基糠醛、7-羟基香豆素、23-羟基乌苏酸、β-谷甾醇、槲皮素、杨梅素、桃叶珊瑚苷、杨梅素-3′-O-β-D-吡喃木糖苷、金丝桃苷。结论所有化合物均为首次从该植物花中分离得到。

OBJECTIVE To study the constituents isolated of the flowers from Rhododendron anthopo-gon D.Don.METHODS The compounds were isolated and purified by chromatography on silica gel.NMR was used to identify the structures of the purified compounds.RESULTS Fourteen compounds were isolated and identified as: triolein,3-hydroxy-3-phenyl-propanamide,methyl oleanolate,ursolic acid,2-hydroxy-4-methoxyl-phenol,5-methoxyfurfural,7-hydroxy-coumarin,23-hydroxy-ursolic acid,β -sitosterol,quercetin,myricetin,ancubin,myricet...