结缔组织病肺间质病变的高分辨率CT特点研究

Research on the feature of HRCT of interstitial lung disease associated with connective tissue diseases

目的研究结缔组织病肺间质病变的高分辨率电子计算机断层成像(HRCT)特点。方法收集HRCT检查提示存在肺间质病变的住院患者共750例,根据其临床资料,将入选的461例患者分为结缔组织病组(CTD组)、可疑结缔组织病组(sCTD组)和特发性间质性肺炎组(IIP组),比较其HRCT表现。结果 461例患者中CTD组79例(10.53%),sCTD组70例(9.33%),IIP组312例(41.60%)。三组之间HRCT的主要肺间质病变表现差异无统计学意义。结论结缔组织病在肺间质病变中占一定的比例,对HRCT发现的肺间质病变应进行结缔组织病的相关检查以免漏诊、误诊。

Objective To investigate the feature of HRCT images of interstitial lung disease( ILD) associated with connective tissue diseases( CTD). Methods 750 patients with ILD recognized by HRCT were studied with their clinical data and were divided into three groups,connective tissue group( CTD group) ,suspected connective tissue group( sCTD group) and idiopathic interstitial pneumonia group( IIP group). Features of HRCT were compared among these three groups. Results 79( 10. 53% ) patients with CTD,70( 9. 33% ) patients with sCTD,312( 41. 60% ) patients with IIP were found. No difference in main HRCT manifestations was found among these three groups. Conclusions As an important proportion of ILD,CTD-ILD should be considered when ILD is recognized by HRCT to avoid missed diagnosis and misdiagnosis.