游泳运动对生长期大鼠长骨生长的影响

Effects of Swimming on Long Bone Growth of Rats

为探讨游泳运动对快速生长期大鼠长骨生长的影响作用,将16只5周龄雌性SD大鼠随机分为对照组和游泳运动组,游泳运动组大鼠进行每天一次,每周5天,为期9周的游泳运动。测定大鼠胫骨骨量、骨形态计量学和生物力学等方面的指标,发现:游泳运动组大鼠胫骨骨量各项指标和对照组间均无显著性差异,骨小梁体积、骨小梁平均宽度、皮质骨厚度、类骨质表面积和类骨质厚度均极显著高于对照组,侵蚀表面积和骨小梁分离度则极显著小于对照组,最大变形和弹性变形显著高于对照组,弹性载荷极显著地高于对照组。这些结果表明:适宜的游泳运动能够通过促进骨形成作用,抑制骨吸收作用促进骨量累积,并能够改善骨的机械性能。

The purpose of this study is to examine the effects of swimming on long bone growth of female rats during rapid growing period.16 female SD rats(5-week old) were randomly assigned to control group and exercise group.The exercise group underwent 9 weeks swimming exercise,5 times a week.The tibiaes parameters of mineralization,histomorphometry and mechanical properties were measured.The result indicate that 9-week swimming exercise can significantly increase BV/TV%,Tb.Th,Os/Bs,O.Th,Tb.Th and Os/Bs,significantly decrease the tibiaes' Tb.Sp and Es/Bs,and also significantly increase bending deformation,maximum deformation and elastic load,but no significantly difference between two groups' bone mineralization.The data above suggest that appropriate swimming can simulate bone formation and suppress bone restoration,and it also can improve long bones mechanic performance,so it have a positive effect on long bone growth.