摘要
目的:探讨皮肤平滑肌肉瘤的临床病理特点和诊断要点及预后。方法:对2例皮肤平滑肌肉瘤组织病理学、免疫组化观察,并复习相关文献。结果:例1为皮下平滑肌肉瘤,具有结节型的生长形态,瘤细胞丰富,异型性较大,核分裂活跃;例2为真皮平滑肌肉瘤,具有弥漫型的生长形态,瘤细胞较少,分化好,核分裂象不明显。免疫组化2例均表达SMA、MSA、Vim,1例灶性表达Desmin。2例随访迄今均无复发及转移。结论:皮肤平滑肌肉瘤少见,可分为真皮和皮下两种类型,两者具有不同的组织起源和预后特点,我们要注意区分,诊断除核分裂象计数外,尚需进行综合评估,对某些病例建议采用恶性潜能未定的平滑肌肉瘤的诊断,治疗首选外科手术切除。
Objective: To investigate the clinic pathological features diagnosis main point and prognosis of cutaneous leiomyosarcoma(CLMS).Methods: Histopathology,immunohistochemical stainings observation were analyzed in two cases of CLMS and the related literatures were reviewed.Results: Case 1 was subcutaneous leiomyosarcoma with tubercular growth pattern,rich tumor cell,big heterogeneous type,active mitotic;Case 2 was dermis leiomyosarcoma with diffuse growth pattern,few tumor cell,well differentiated,no more mito...
出处
《华西医学》
CAS
2009年第12期3142-3144,共3页
West China Medical Journal
关键词
皮肤平滑肌肉瘤
组织发生
临床病理学
预后
cutaneous leiomyosarcoma
tissue origin
clinic pathology
prognosis
